Acetic Acid → 1-Methoxycarbonyl-2-isopropylidene hydrazine

HRID 79865

반응식

HRID 79865 반응식
[CH3:1][O:2][C:3]([NH:5][NH2:6])=[O:4].C(O)(=O)C.O.[CH3:12][C:13]([CH3:15])=O>>[CH3:1][O:2][C:3]([NH:5][N:6]=[C:13]([CH3:15])[CH3:12])=[O:4]

참가 물질

5

반응물 4

HCID 176Acetic AcidHCID 180AcetoneHCID 962WaterHCID 80519Methyl carbazate

생성물 1

HCID 9095211-Methoxycarbonyl-2-isopropylidene hydrazine수율 89%

실험 절차

Hydrazinecarboxylic acid methyl ester (5.01 g) were dissolved in acetone (28 mL), and acetic acid (0.0636 mL) was added. The reaction mixture was stirred at room temperature for 24 hours. Water (50 mL) was added, and mixture was extracted three times with DCM (50 mL) and evaporated under vacuum, giving N′-Isopropylidene-hydrazine-carboxylic acid methyl ester (6.45 g, 89%).

후처리

  1. extractionmixture was extracted three times with DCM (50 mL)
  2. customevaporated under vacuum

출처 및 근거

ORD 기록
ord-d0f21b28363a4a90a006665835618b39
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08841278B2

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