[2-chloro-5-(2H-pyrazol-3-yl)-pyrimidin-4-yl]-(3-morpholin-4-yl-propyl)-amine → (RS)-N-(isopropylcarbamoyl)-S-(4-{4-(3-morpholin-4-yl-propylamino)-5-(2H-pyrazol-3-yl)-pyrimidin-2-ylamino}phenyl)-S-methylsulfoximide

반응식

[Cl:1][c:2]1[n:3][cH:4][c:5](-[c:18]2[nH:19][n:20][cH:21][cH:22]2)[c:6]([NH:8][CH2:9][CH2:10][CH2:11][N:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[n:7]1.[NH2:23][c:24]1[cH:25][cH:26][c:27]([S:30](=[O:31])(=[N:32][C:33]([NH:34][CH:35]([CH3:36])[CH3:37])=[O:38])[CH3:39])[cH:28][cH:29]1>>[c:2]1([NH:23][c:24]2[cH:25][cH:26][c:27]([S:30](=[O:31])(=[N:32][C:33]([NH:34][CH:35]([CH3:36])[CH3:37])=[O:38])[CH3:39])[cH:28][cH:29]2)[n:3][cH:4][c:5](-[c:18]2[nH:19][n:20][cH:21][cH:22]2)[c:6]([NH:8][CH2:9][CH2:10][CH2:11][N:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[n:7]1

참가 물질

반응물 2

HCID 58985683[2-chloro-5-(2H-pyrazol-3-yl)-pyrimidin-4-yl]-(3-morpholin-4-yl-propyl)-amine

HCID 59550859HCID 59550859, 화합물

생성물 1

HCID 58985642(RS)-N-(isopropylcarbamoyl)-S-(4-{4-(3-morpholin-4-yl-propylamino)-5-(2H-pyrazol-3-yl)-pyrimidin-2-ylamino}phenyl)-S-methylsulfoximide

출처 및 근거

ORD 기록: ord-a2311d1c8bf542499ce85b470f5be273
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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