2-(((3-(Trifluoromethyl)phenyl)methyl)sulfonyl)acetonitrile → 2-(3-Trifluoromethyl-phenylmethanesulfonyl)-4-trifluoromethylsulfanyl-butyronitrile

HRID 80405노트

반응식

HRID 80405 반응식
[F:1][C:2]([F:17])([F:16])[C:3]1[CH:4]=[C:5]([CH2:9][S:10]([CH2:13][C:14]#[N:15])(=[O:12])=[O:11])[CH:6]=[CH:7][CH:8]=1.[F:18][C:19]([S:22][CH2:23][CH2:24]OS(C(F)(F)F)(=O)=O)([F:21])[F:20]>>[F:17][C:2]([F:1])([F:16])[C:3]1[CH:4]=[C:5]([CH2:9][S:10]([CH:13]([CH2:24][CH2:23][S:22][C:19]([F:21])([F:20])[F:18])[C:14]#[N:15])(=[O:12])=[O:11])[CH:6]=[CH:7][CH:8]=1

참가 물질

3

반응물 2

HCID 27824342-(((3-(Trifluoromethyl)phenyl)methyl)sulfonyl)acetonitrileHCID 252420282-(Trifluoromethylthio)ethyl Trifluoromethanesulfonate

생성물 1

HCID 866732702-(3-Trifluoromethyl-phenylmethanesulfonyl)-4-trifluoromethylsulfanyl-butyronitrile

실험 절차

Compound II-5 was prepared from (3-trifluoromethyl-phenylmethanesulfonyl)-acetonitrile and trifluoro-methanesulfonic acid 2-trifluoromethylsulfanyl-ethyl ester as described for compound II-1.

출처 및 근거

ORD 기록
ord-ff159c090ba3454aa06da4364b76fc74
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08846569B2

반응 노트

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