(2-Methoxypyridin-3-yl)boronic acid → 4-(2'-Methoxy-3,3'-bipyridin-5-yl)-1,4-diazatricyclo[4.3.1.13,8]undecane

HRID 80447

반응식

HRID 80447 반응식
Br[C:2]1[CH:3]=[C:4]([N:8]2[CH2:16][CH:15]3[CH2:17][N:11]4[CH2:12][CH:13]([CH2:18][CH:9]2[CH2:10]4)[CH2:14]3)[CH:5]=[N:6][CH:7]=1.[CH3:19][O:20][C:21]1[C:26](B(O)O)=[CH:25][CH:24]=[CH:23][N:22]=1>>[CH3:19][O:20][C:21]1[C:26]([C:2]2[CH:7]=[N:6][CH:5]=[C:4]([N:8]3[CH2:16][CH:15]4[CH2:17][N:11]5[CH2:12][CH:13]([CH2:18][CH:9]3[CH2:10]5)[CH2:14]4)[CH:3]=2)=[CH:25][CH:24]=[CH:23][N:22]=1

참가 물질

3

반응물 2

HCID 2762709(2-Methoxypyridin-3-yl)boronic acidHCID 866492494-(5-Bromopyridin-3-yl)-1,4-diazatricyclo[4.3.1.13,8]undecane

생성물 1

HCID 866492584-(2'-Methoxy-3,3'-bipyridin-5-yl)-1,4-diazatricyclo[4.3.1.13,8]undecane

실험 절차

The title compound was prepared from the product of Example 65A and 2-methoxypyridin-3-ylboronic acid according to General Method B: LC-MS Method D (ESI+) m/z 337.0 (M+H)+, retention time 1.24 minutes.

출처 및 근거

ORD 기록
ord-8a2e67f357da48dcb7de9b53a28c7987
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08846661B2

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