1-(4-Amino-3-fluorophenyl)pyrazin-2(1H)-one → 3-{[(5-chloro-thiophene-2-carbonyl)-amino]-methyl}-[1,2,4]oxadiazole-5-carboxylic acid [2-fluoro-4-(2-oxo-2H-pyrazine-1-yl)-phenyl]-amide

반응식

[CH2:1]([O:2][C:4](=[O:5])[c:6]1[n:7][c:8]([CH2:11][NH:12][C:13](=[O:14])[c:15]2[s:16][c:17]([Cl:20])[cH:18][cH:19]2)[n:9][o:10]1)[CH3:3].[NH2:21][c:22]1[c:23]([F:35])[cH:24][c:25](-[n:28]2[c:29](=[O:34])[cH:30][n:31][cH:32][cH:33]2)[cH:26][cH:27]1>>[C:4](=[O:5])([c:6]1[n:7][c:8]([CH2:11][NH:12][C:13](=[O:14])[c:15]2[s:16][c:17]([Cl:20])[cH:18][cH:19]2)[n:9][o:10]1)[NH:21][c:22]1[c:23]([F:35])[cH:24][c:25](-[n:28]2[c:29](=[O:34])[cH:30][n:31][cH:32][cH:33]2)[cH:26][cH:27]1

참가 물질

반응물 2

HCID 230867741-(4-Amino-3-fluorophenyl)pyrazin-2(1H)-one

HCID 593029563-{[(5-Chloro-thiophene-2-carbonyl)-amino]-methyl}-[1,2,4]oxadiazole-5-carboxylic acid ethyl ester

생성물 1

HCID 249676303-{[(5-chloro-thiophene-2-carbonyl)-amino]-methyl}-[1,2,4]oxadiazole-5-carboxylic acid [2-fluoro-4-(2-oxo-2H-pyrazine-1-yl)-phenyl]-amide

출처 및 근거

ORD 기록: ord-c27c85f3fef7418f885dcdbf299b18de
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…