Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → Methyl 2-amino-5-(2,2-difluoroethoxy)benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | Methyl 5-(2,2-difluoroethoxy)-2-nitrobenzoate | HCID 59587324 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | Methyl 2-amino-5-(2,2-difluoroethoxy)benzoate | HCID 59587097 | — |
반응 단계
21 g of methyl 5-(2,2-difluoroethoxy)-2-nitrobenzoate obtained in stage 3.1 and 1 g of Pd/C (10%) in a mixture of 300 ml of AcOEt, 50 ml of EtOH and 5 ml of AcOH are stirred at AT under a hydrogen atmosphere for 24 h 00.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846654B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-9d6b020ecd0a446cb2085ef5076c8e8f |
| 출처 메모 | uspto-grants-2014_09 |