Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → 2-Fluoro-4-(3-diethylamino-1-propoxy)nitrobenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 3-(Diethylamino)-1-propanol | HCID 12159 | — |
| 반응물 | Methanesulfonate | HCID 85257 | — |
| 반응물 | 3-Fluoro-4-nitrophenol | HCID 520948 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 2-Fluoro-4-(3-diethylamino-1-propoxy)nitrobenzene | HCID 22014733 | — |
반응 단계
A solution of 3-fluoro-4-nitrophenol (2 mmol) and methanesulfonate of 3-diethylamino-1-propanol (2.5 mmol) in DMF (4 mL) is added with K2CO3 (4 mmol) and heated following the general procedure III (Step A). The product, 2-fluoro-4-(3-diethylamino-1-propoxy)nitrobenzene is obtained (470 mg) after purification using silica gel column chromatography.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07087632B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-f375c00562a24af688c5e95063e27f6d |
| 출처 메모 | uspto-grants-2006_08 |