참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Nitric Acid | HCID 944 | — |
| 반응물 | 2-Acetamido-6-methylbenzoic acid | HCID 2801400 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 6-Acetylamino-2-methyl-3-nitro-benzoic acid | HCID 15283171 | — |
반응 단계
271 ml of 98% nitric acid are initially taken at -5° C. and 106 g (0.55 mol) of the 2-methyl-6-acetamidobenzoic acid prepared in 1. are added in portions. After stirring at 10° C. for one hour, the reaction mixture is poured into a mixture of 540 g of ice and 270 ml of water. The deposited precipitate is filtered off with suction, washed with water and dried under reduced pressure at 50° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05723415 |
|---|
| 출처 데이터셋 | uspto-grants-1998_03 |
|---|
| ORD ID | ord-036dc1bd98f447088e22557193b51876 |
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| 출처 메모 | uspto-grants-1998_03 |
|---|
