Dichloromethane → 3-(2-Thiazolyl)piperidine

반응식

[Cl:19][CH2:20][Cl:21].[F:22][C:23]([F:24])([F:25])[C:26]([OH:27])=[O:28].[s:1]1[c:2]([CH:6]2[CH2:7][N:8]([C:12]([O:13][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:18])[CH2:9][CH2:10][CH2:11]2)[n:3][cH:4][cH:5]1>>[s:1]1[c:2]([CH:6]2[CH2:7][NH:8][CH2:9][CH2:10][CH2:11]2)[n:3][cH:4][cH:5]1

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 534852273-(2-Thiazolyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester

생성물 1

HCID 242618023-(2-Thiazolyl)piperidine

출처 및 근거

ORD 기록: ord-d75f3a3186f749ae81fcb26c605a6703
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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