Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Amino-3,5-dibromopyrazine → 7-Bromo-1-[5-chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrazino[2,3-b]pyrazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Amino-3,5-dibromopyrazine | HCID 620004 | — |
| 반응물 | 2-Chloro-3,6-difluorobenzylamine | HCID 2773545 | — |
| 반응물 | 5-Chloro-2-(trifluoromethyl)benzylamine | HCID 20111708 | — |
| 생성물 | 7-Bromo-1-[5-chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrazino[2,3-b]pyrazine | HCID 86659426 | — |
반응 단계
7-bromo-1-[5-chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrazino[2,3-b]pyrazine was prepared as described in Example 1 from 2-amino-3,5-dibromopyrazine as described in Example 1 by replacing 2-chloro-3,6-difluorobenzylamine in step 1 with 5-chloro-2-trifluoromethyl-benzylamine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846664B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-1ecf8e89ab0a4af795315346b97f8ac6 |
| 출처 메모 | uspto-grants-2014_09 |