Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyridine → 3,5-Dimethyl-1-(3-nitrophenyl)-1H-pyrazole-4-carboxylic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | Ethyl 2-acetylacetoacetate | HCID 79063 | — |
| 반응물 | 3-Nitrophenylhydrazinium(1+) chloride | HCID 5464285 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3,5-Dimethyl-1-(3-nitrophenyl)-1H-pyrazole-4-carboxylic acid ethyl ester | HCID 656969 | — |
반응 단계
Similar to Example 1, m-nitrophenylhydrazine hydrochloride (10 mmol, 1.9 g) and 2-acetyl-3-oxo-butyric acid ethyl ester (10 mmol, 1.7 g) were mixed in a 50% solution of pyridine in ethanol. A precipitate was formed in the reaction medium, and was collected by filtration. Analysis confirmed synthesis of the named product, m.p., 107.7° C.–109.2° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07087634B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-429914abd99c47c1b147ebf79f741665 |
| 출처 메모 | uspto-grants-2006_08 |