4-Amino-1-Boc-piperidine → 4-{[4-(2-Cyclopropylmethoxy-4-methoxy-phenyl)-5H-pyrrolo[3,2-d]pyrimidine-7-carbonyl]-amino}-piperidine-1-carboxylic acid tert-butyl ester

반응식

[C:26]([CH3:27])([CH3:28])([CH3:29])[O:30][C:31](=[O:32])[N:33]1[CH2:34][CH2:35][CH:36]([NH2:39])[CH2:37][CH2:38]1.[CH:1]1([CH2:4][O:5][c:6]2[c:7](-[c:14]3[c:15]4[c:16]([n:17][cH:18][n:19]3)[c:20]([C:23](=[O:24])[OH:25])[cH:21][nH:22]4)[cH:8][cH:9][c:10]([O:12][CH3:13])[cH:11]2)[CH2:2][CH2:3]1>>[CH:1]1([CH2:4][O:5][c:6]2[c:7](-[c:14]3[c:15]4[c:16]([n:17][cH:18][n:19]3)[c:20]([C:23](=[O:24])[NH:39][CH:36]3[CH2:35][CH2:34][N:33]([C:31]([O:30][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:32])[CH2:38][CH2:37]3)[cH:21][nH:22]4)[cH:8][cH:9][c:10]([O:12][CH3:13])[cH:11]2)[CH2:2][CH2:3]1

참가 물질

반응물 2

HCID 12682914-Amino-1-Boc-piperidine

HCID 668660964-(2-Cyclopropylmethoxy-4-methoxy-phenyl)-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid

생성물 1

HCID 668661244-{[4-(2-Cyclopropylmethoxy-4-methoxy-phenyl)-5H-pyrrolo[3,2-d]pyrimidine-7-carbonyl]-amino}-piperidine-1-carboxylic acid tert-butyl ester

출처 및 근거

ORD 기록: ord-b95006348cb54b95a2fe6373b6de4e1c
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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