Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,5-Dimethylisoxazole-4-sulfonyl chloride → 4-(4-(4-((6-(1H-Tetrazol-1-yl)pyridin-3-yloxy)methyl)-2H-1,2,3-triazol-2-yl)piperidin-1-ylsulfonyl)-3,5-dimethylisoxazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3,5-Dimethylisoxazole-4-sulfonyl chloride | HCID 2736319 | — |
| 반응물 | 5-((2-(piperidin-4-yl)-2H-1,2,3-triazol-4-yl)methoxy)-2-(1H-tetrazol-1-yl)pyridine hydrochloride | HCID 68746624 | — |
| 생성물 | 4-(4-(4-((6-(1H-Tetrazol-1-yl)pyridin-3-yloxy)methyl)-2H-1,2,3-triazol-2-yl)piperidin-1-ylsulfonyl)-3,5-dimethylisoxazole | HCID 25174423 | — |
반응 단계
The title compound was synthesized using Intermediate 15 and 3,5-dimethylisoxazole-4-sulfonyl chloride in a similar manner as described in Example 39. 1H NMR (DMSO-d6): δ 10.07 (1H, s), 8.41 (1H, d), 8.00 (1H, d), 7.94 (1H, s), 7.86 (1H, dd), 5.34 (2H, s), 4.65 (1H, m), 3.68 (2H, m), 2.86 (2H, m), 2.61 (3H, s), 2.33 (3H, s), 2.24 (2H, m), 2.00 (2H, m).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846675B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-2b02756a7cda40e39159ac8538f28d64 |
| 출처 메모 | uspto-grants-2014_09 |