8-Azabicyclo(3.2.1)octan-3-one → 8-(5-(Trifluoromethyl)pyrimidin-2-yl)-8-azabicyclo[3.2.1]octan-3-one
반응식
CS([C:5]1[N:10]=[CH:9][C:8]([C:11]([F:14])([F:13])[F:12])=[CH:7][N:6]=1)(=O)=O.[CH:15]12[NH:22][CH:19]([CH2:20][CH2:21]1)[CH2:18][C:17](=[O:23])[CH2:16]2>>[F:12][C:11]([F:14])([F:13])[C:8]1[CH:7]=[N:6][C:5]([N:22]2[CH:15]3[CH2:21][CH2:20][CH:19]2[CH2:18][C:17](=[O:23])[CH2:16]3)=[N:10][CH:9]=1참가 물질
3
실험 절차
The title compound was synthesized from 2-(methylsulfonyl)-5-(trifluoromethyl)pyrimidine and 8-azabicyclo[3.2.1]octan-3-one in a manner similar to that described in Example 9.
출처 및 근거
- ORD 기록
- ord-2c8b74ede8d94be09fa82db0e5d59d0a
- 출처 데이터셋
- uspto-grants-2014_09
- 특허 번호
- US08846675B2
반응 노트
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