Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyridine → 3,5-dimethyl-1-m-tolyl-1H-pyrazole-4-carboxylic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | m-Tolylhydrazinium(1+) chloride | HCID 71562 | — |
| 반응물 | Ethyl 2-acetylacetoacetate | HCID 79063 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3,5-dimethyl-1-m-tolyl-1H-pyrazole-4-carboxylic acid ethyl ester | HCID 9878335 | — |
반응 단계
Similar to Example 1, equimolar amounts of m-tolylhydrazine hydrochloride and 2-acetyl-3-oxo-butyric acid ethyl ester were combined in a solution of a 50% pyridine in ethanol. The resulting oil was purified by flash chromatography to yield the named product as a solid (m.p. 46.5° C.–47.5° C.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07087634B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-10ff9f3ebf424ef1bf07a369dc0fa429 |
| 출처 메모 | uspto-grants-2006_08 |