1,4'-Bipiperidine → 1'-{6-[4-(Methanesulfonyl)phenyl]pyridazin-3-yl}-1,4'-bipiperidine

HRID 80879

반응식

HRID 80879 반응식
Cl[C:2]1[N:3]=[N:4][C:5]([C:8]2[CH:13]=[CH:12][C:11]([S:14]([CH3:17])(=[O:16])=[O:15])=[CH:10][CH:9]=2)=[CH:6][CH:7]=1.[N:18]1([CH:24]2[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]2)[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1>>[CH3:17][S:14]([C:11]1[CH:12]=[CH:13][C:8]([C:5]2[N:4]=[N:3][C:2]([N:27]3[CH2:28][CH2:29][CH:24]([N:18]4[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]4)[CH2:25][CH2:26]3)=[CH:7][CH:6]=2)=[CH:9][CH:10]=1)(=[O:16])=[O:15]

참가 물질

3

반응물 2

HCID 786071,4'-BipiperidineHCID 435838903-Chloro-6-[4-(methanesulfonyl)phenyl]pyridazine

생성물 1

HCID 159513161'-{6-[4-(Methanesulfonyl)phenyl]pyridazin-3-yl}-1,4'-bipiperidine

실험 절차

The title compound was prepared by a similar procedure to that described in Example 1, starting from 3-chloro-6-(4-methanesulfonylphenyl)pyridazine and 4-(piperid-1-yl)piperidine.

출처 및 근거

ORD 기록
ord-77b1bb946d38426cab89fec5450a46ba
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08846677B2

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