3-Chloro-6-(3-fluoro-4-methoxyphenyl)pyridazine → [1-(1-Ethylpropyl)piperidin-4-yl]-[6-(3-fluoro-4-methoxyphenyl)pyridazin-3-yl]amine

HRID 80889노트

반응식

HRID 80889 반응식
Cl[C:2]1[N:3]=[N:4][C:5]([C:8]2[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[C:10]([F:16])[CH:9]=2)=[CH:6][CH:7]=1.[NH2:17][CH:18]1[CH2:23][CH2:22][N:21]([CH:24]([CH2:27][CH3:28])[CH2:25][CH3:26])[CH2:20][CH2:19]1>>[CH2:25]([CH:24]([N:21]1[CH2:22][CH2:23][CH:18]([NH:17][C:2]2[N:3]=[N:4][C:5]([C:8]3[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[C:10]([F:16])[CH:9]=3)=[CH:6][CH:7]=2)[CH2:19][CH2:20]1)[CH2:27][CH3:28])[CH3:26]

참가 물질

3

반응물 2

HCID 203982843-Chloro-6-(3-fluoro-4-methoxyphenyl)pyridazineHCID 246980774-Amino-1-(1-ethylpropyl)piperidine

생성물 1

HCID 15951319[1-(1-Ethylpropyl)piperidin-4-yl]-[6-(3-fluoro-4-methoxyphenyl)pyridazin-3-yl]amine

실험 절차

The title compound was prepared by a similar procedure to that described in Example 1, starting from 3-chloro-6-(4-methoxy-3-fluorophenyl)pyridazine and 4-amino-1-(1-ethylpropyl)piperidine.

출처 및 근거

ORD 기록
ord-504e7116aa654e8fb0bca3cfe1ff6014
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08846677B2

반응 노트

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