참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | L-Tryptophan | HCID 6305 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 용매 | 1-Butanol | HCID 263 | — |
| 생성물 | Tryptophan butyl ester | HCID 11666077 | 181.9% |
반응 단계
L-Tryptophane (5 g; 24.5 mmol) and thionyl chloride (73.5 mmol; 5.3 ml) were dissolved in n-butanol (80 ml) and stirred at 100° C. over night. The product 5 precipitated after cooling to room temperature, was filtered off and washed with ice cold butanol and petrol ether. The product was dried at the oil pump, yielding 5.8 g of 5 (91%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08846682B2 |
|---|
| 출처 데이터셋 | uspto-grants-2014_09 |
|---|
| ORD ID | ord-4ed8fe63fe6941eca33ae882bbf034d6 |
|---|
| 출처 메모 | uspto-grants-2014_09 |
|---|
