Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 8122생성일: 2026년 10월 24일
Dimethyl(methylene)ammounium iodide → 3-dimethylaminomethyl-1H-indole-4-carboxylic acid methyl ester hydroiodide
https://huagongshe.com/ko/reaction/8122
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Dimethyl(methylene)ammounium iodide | HCID 2724133 | — |
| 반응물 | methyl 1H-indole-4-carboxylate | HCID 2733668 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 3-dimethylaminomethyl-1H-indole-4-carboxylic acid methyl ester hydroiodide | HCID 69518011 | — |
반응 단계
Methyl indole-4-carboxylate (7.0 g, 40 mmol) and Eschenmoser's salt (N,N-dimethylmethyleneammonium iodide; 7.8 g, 42 mmol) are combined in 130 ml of acetic acid. After heating at 65° C. for 2 hours, the reaction mixture is concentrated in vacuo. The resulting solid is triturated with ethyl acetate, filtered and dried in vacuo to give 3-dimethylaminomethyl-1H-indole-4-carboxylic acid methyl ester hydroiodide in quantitative yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US07087635B2 |
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| 출처 데이터셋 | uspto-grants-2006_08 |
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| ORD ID | ord-c7d2f163f53541348b1ec62b194c7f1c |
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| 출처 메모 | uspto-grants-2006_08 |
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