Dichloromethane → 3-[8-(2,6-difluorophenyl)-2-(methylsulfinyl)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-4-yl]-4-methyl-N-(phenylmethyl)benzamide

HRID 812911노트

반응식

[CH3:53][CH2:54][O:55][C:56]([CH3:57])=[O:58].[Cl:50][CH2:51][Cl:52].[F:1][c:2]1[c:3](-[n:9]2[c:10](=[O:38])[cH:11][cH:12][c:13]3[c:14]2[n:15][c:16]([S:36][CH3:37])[n:17][c:18]3-[c:19]2[cH:20][c:21]([C:22](=[O:23])[NH:24][CH2:25][c:26]3[cH:27][cH:28][cH:29][cH:30][cH:31]3)[cH:32][cH:33][c:34]2[CH3:35])[c:4]([F:8])[cH:5][cH:6][cH:7]1.[OH:39][O:40][C:41]([c:42]1[cH:43][c:44]([Cl:45])[cH:46][cH:47][cH:48]1)=[O:49]>>[F:1][c:2]1[c:3](-[n:9]2[c:10](=[O:38])[cH:11][cH:12][c:13]3[c:14]2[n:15][c:16]([S:36]([CH3:37])=[O:39])[n:17][c:18]3-[c:19]2[cH:20][c:21]([C:22](=[O:23])[NH:24][CH2:25][c:26]3[cH:27][cH:28][cH:29][cH:30][cH:31]3)[cH:32][cH:33][c:34]2[CH3:35])[c:4]([F:8])[cH:5][cH:6][cH:7]1