N-(5-fluoro-2-oxo-2,3-dihydro-1H-indol-6-yl)-2-hydroxy-2-methyl-propionamide → N-{3-[5-(2-diethylamino-ethyl)-3-methyl-4-oxo-1,4,5,6,7,8-hexahydro-pyrrolo[3,2-c]azepin-2-ylmethylene]-5-fluoro-2-oxo-2,3-dihydro-1H-indol-6-yl}-2-hydroxy-2-methyl-propionamide
반응식
[CH2:1]([CH3:2])[N:3]([CH2:4][CH2:5][N:6]1[C:7](=[O:19])[c:8]2[c:9]([nH:13][c:14]([CH:17]=[O:18])[c:15]2[CH3:16])[CH2:10][CH2:11][CH2:12]1)[CH2:20][CH3:21].[F:22][c:23]1[cH:24][c:25]2[c:29]([cH:30][c:31]1[NH:32][C:33]([C:34]([CH3:35])([CH3:36])[OH:37])=[O:38])[NH:28][C:27](=[O:39])[CH2:26]2>>[CH2:1]([CH3:2])[N:3]([CH2:4][CH2:5][N:6]1[C:7](=[O:19])[c:8]2[c:9]([nH:13][c:14]([CH:17]=[C:26]3[c:25]4[cH:24][c:23]([F:22])[c:31]([NH:32][C:33]([C:34]([CH3:35])([CH3:36])[OH:37])=[O:38])[cH:30][c:29]4[NH:28][C:27]3=[O:39])[c:15]2[CH3:16])[CH2:10][CH2:11][CH2:12]1)[CH2:20][CH3:21]참가 물질
3
반응물 2
생성물 1
출처 및 근거
- ORD 기록
- ord-02f9ae855b8049ed8139c027f97d52b8
- 출처 데이터셋
- Test data from https://doi.org/10.1039/C8SC04228D
반응 노트
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