Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Methyl-5-(morpholin-4-ylsulphonyl)benzeneboronic acid → 3-Amino-6-[2-methyl-5-(morpholine-4-sulfonyl)-phenyl]-pyrazine-2-carboxylic acid methoxy-methyl amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Methyl-5-(morpholin-4-ylsulphonyl)benzeneboronic acid | HCID 44119554 | — |
| 반응물 | 3-Amino-6-(3,4-dichloro-phenyl)-pyrazine-2-carboxylic acid methoxy-methyl amide | HCID 86634542 | — |
| 생성물 | 3-Amino-6-[2-methyl-5-(morpholine-4-sulfonyl)-phenyl]-pyrazine-2-carboxylic acid methoxy-methyl amide | HCID 86634543 | — |
반응 단계
This compound is prepared in an analogous manner to intermediate B substituting 3,4 dichlorophenyl boronic acid with 2-methyl-5-(N-morpholinylsulfonyl)phenyl boronic acid in step 2. The title compound is obtained as an off-white solid. [M+H]+ 422.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846687B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-9e5889ab11b94bd49176e246e6ed9dbc |
| 출처 메모 | uspto-grants-2014_09 |