5-Ethynylpyridin-2-amine → 5-[8-Fluoro-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridin-3-ylethynyl]-pyridin-2-ylamine

반응식

[C:22](#[CH:23])[c:24]1[cH:25][cH:26][c:27]([NH2:30])[n:28][cH:29]1.[F:1][c:2]1[c:3]2[n:4]([cH:5][c:6](-[c:8]3[cH:9][cH:10][c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]3)[cH:7]1)[c:18]([I:21])[cH:19][n:20]2>>[F:1][c:2]1[c:3]2[n:4]([cH:5][c:6](-[c:8]3[cH:9][cH:10][c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]3)[cH:7]1)[c:18]([C:23]#[C:22][c:24]1[cH:25][cH:26][c:27]([NH2:30])[n:28][cH:29]1)[cH:19][n:20]2

참가 물질

반응물 2

HCID 219548275-Ethynylpyridin-2-amine

HCID 670012068-Fluoro-3-iodo-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridine

생성물 1

HCID 670011215-[8-Fluoro-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridin-3-ylethynyl]-pyridin-2-ylamine

출처 및 근거

ORD 기록: ord-ae26e899a100440c8d0e5145be014206
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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