3-(Aminomethyl)benzeneboronic acid, N-BOC protected → [3-(2-Amino-6-methyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl)-benzyl]-carbamic acid tert-butyl ester

반응식

[Br:1][c:2]1[c:3]2[n:4]([cH:5][c:6]([CH3:8])[cH:7]1)[n:9][c:10]([NH2:12])[n:11]2.[C:13]([CH3:14])([CH3:15])([CH3:16])[O:17][C:18](=[O:19])[NH:20][CH2:21][c:22]1[cH:23][c:24]([B:28]([OH:29])[OH:30])[cH:25][cH:26][cH:27]1>>[c:2]1(-[c:24]2[cH:23][c:22]([CH2:21][NH:20][C:18]([O:17][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:19])[cH:27][cH:26][cH:25]2)[c:3]2[n:4]([cH:5][c:6]([CH3:8])[cH:7]1)[n:9][c:10]([NH2:12])[n:11]2

참가 물질

반응물 2

HCID 36846863-(Aminomethyl)benzeneboronic acid, N-BOC protected

HCID 214643388-Bromo-6-methyl-[1,2,4]triazolo[1,5-a]pyridin-2-amine

생성물 1

HCID 67335256[3-(2-Amino-6-methyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl)-benzyl]-carbamic acid tert-butyl ester

출처 및 근거

ORD 기록: ord-2ad62cff5eaa40c1b09ffbc575eadff7
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…