Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzenamine, 4-(4-morpholinyl)- → (E)-N-(3-(2-(4-morpholinophenylamino)pyrimidin-4-ylthio)phenyl)but-2-enamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzenamine, 4-(4-morpholinyl)- | HCID 75655 | — |
| 반응물 | (E)-N-(3-(2-chloropyrimidin-4-ylthio)phenyl)but-2-enamide | HCID 86645570 | — |
| 생성물 | (E)-N-(3-(2-(4-morpholinophenylamino)pyrimidin-4-ylthio)phenyl)but-2-enamide | HCID 59491799 | 69.6% |
반응 단계
In a procedure analogous to Example 8, reaction of (E)-N-(3-(2-chloropyrimidin-4-ylthio)phenyl)but-2-enamide (103 mg, 0.26 mmol) and 4-morpholinoaniline (47 mg, 0. 26 mmol) furnished the product (81 mg, 69%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846704B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-dcdee2642e314ceabf4d9cee060e0563 |
| 출처 메모 | uspto-grants-2014_09 |