Cyanoacetic acid → HCID 59491624, 화합물

HRID 81718

반응식

HRID 81718 반응식
[C:1]1([S:7][C:8]2[CH:13]=[CH:12][N:11]=[C:10]([NH:14][C:15]3[CH:20]=[CH:19][CH:18]=[C:17]([NH2:21])[CH:16]=3)[N:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:22]([CH2:24][C:25](O)=[O:26])#[N:23]>>[C:1]1([S:7][C:8]2[CH:13]=[CH:12][N:11]=[C:10]([NH:14][C:15]3[CH:16]=[C:17]([NH:21][C:25](=[O:26])[CH2:24][C:22]#[N:23])[CH:18]=[CH:19][CH:20]=3)[N:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

3

반응물 2

HCID 9740Cyanoacetic acidHCID 68746426N1-(4-(phenylthio)pyrimidin-2-yl)benzene-1,3-diamine

생성물 1

HCID 59491624HCID 59491624, 화합물수율 47.1%

실험 절차

In a procedure analogous to Example 15, reaction of N1-(4-(phenylthio)pyrimidin-2-yl)benzene-1,3-diamine (80 mg, 0.27 mmol) and cyanoacetic acid (46 mg, 0.54 mmol) furnished the product (46 mg, 47%).

출처 및 근거

ORD 기록
ord-ab886262780d4573b96b9dc208bd1ba5
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08846704B2

연결된 노트

불러오는 중…