Acrylic Acid → HCID 24989915, 화합물

HRID 81719

반응식

HRID 81719 반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[S:7][C:8]1[CH:13]=[CH:12][N:11]=[C:10]([NH:14][C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([NH2:21])[CH:16]=2)[N:9]=1.[C:22](O)(=[O:25])[CH:23]=[CH2:24]>>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[S:7][C:8]1[CH:13]=[CH:12][N:11]=[C:10]([NH:14][C:15]2[CH:16]=[C:17]([NH:21][C:22](=[O:25])[CH:23]=[CH2:24])[CH:18]=[CH:19][CH:20]=2)[N:9]=1

참가 물질

3

반응물 2

HCID 6581Acrylic AcidHCID 68749996N1-(4-(pyridin-2-ylthio)pyrimidin-2-yl)benzene-1,3-diamine

생성물 1

HCID 24989915HCID 24989915, 화합물수율 43%

실험 절차

In a procedure analogous to Example 15, reaction of N1-(4-(pyridin-2-ylthio)pyrimidin-2-yl)benzene-1,3-diamine (35 mg, 0.12 mmol) and acrylic acid (16 μL, 0.24 mmol) furnished the product (18 mg, 43%).

출처 및 근거

ORD 기록
ord-7f4e5cc36887435cbbdc295e9f320425
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08846704B2

연결된 노트

불러오는 중…