2-Bromoacetamidopyridine → 1'-{[6-Chloro-1-(2-oxo-2-pyridin-2-ylethyl)-1H-indol-3-yl]carbonyl}-5-fluoro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one

HRID 818698

반응식

HRID 818698 반응식
[Br:29][CH2:30][C:31](=[O:32])[c:33]1[n:34][cH:35][cH:36][cH:37][cH:38]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][C:16]4([O:17][C:18](=[O:26])[c:19]5[c:20]4[cH:21][cH:22][c:23]([F:25])[cH:24]5)[CH2:27][CH2:28]3)[cH:7][nH:8][c:9]2[cH:10]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][C:16]4([O:17][C:18](=[O:26])[c:19]5[c:20]4[cH:21][cH:22][c:23]([F:25])[cH:24]5)[CH2:27][CH2:28]3)[cH:7][n:8]([CH2:30][C:31](=[O:32])[c:33]3[n:34][cH:35][cH:36][cH:37][cH:38]3)[c:9]2[cH:10]1

참가 물질

3

반응물 2

HCID 383842-BromoacetamidopyridineHCID 596576231'-[(6-chloro-1H-indol-3-yl)carbonyl]-5-fluoro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one

생성물 1

HCID 596576051'-{[6-Chloro-1-(2-oxo-2-pyridin-2-ylethyl)-1H-indol-3-yl]carbonyl}-5-fluoro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one

출처 및 근거

ORD 기록
ord-9d3f46d0d5744e0ca85c967d60a8da7f
출처 데이터셋
Test data from https://doi.org/10.1039/C8SC04228D

연결된 노트

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