Methanol → 4'-(2,4-Diamino-pyrimidin-5-ylmethyl)-2',6'-diethoxy-biphenyl-4-ol

반응식

[CH2:1]([O:2][c:3]1[cH:4][c:5]([CH2:13][c:14]2[c:15]([NH2:16])[n:17][c:18]([NH2:19])[n:20][cH:21]2)[cH:6][c:7]([O:8][CH2:9][CH3:10])[c:11]1[I:12])[CH3:22].[CH2:23]([CH3:24])[O:25][c:26]1[c:27](-[c:44]2[cH:45][cH:46][c:47]([O:50][CH2:51][O:52][CH3:53])[cH:48][cH:49]2)[c:28]([O:41][CH2:42][CH3:43])[cH:29][c:30]([CH2:32][c:33]2[c:34]([NH2:40])[n:35][c:36]([NH2:39])[n:37][cH:38]2)[cH:31]1.[CH3:54][OH:55]>>[CH2:23]([CH3:24])[O:25][c:26]1[c:27](-[c:44]2[cH:45][cH:46][c:47]([OH:50])[cH:48][cH:49]2)[c:28]([O:41][CH2:42][CH3:43])[cH:29][c:30]([CH2:32][c:33]2[c:34]([NH2:40])[n:35][c:36]([NH2:39])[n:37][cH:38]2)[cH:31]1

참가 물질

반응물 3

HCID 887Methanol

HCID 226368235-(2,6-Diethoxy-4'-methoxymethoxy-biphenyl-4-ylmethyl)-pyrimidine-2,4-diamine

HCID 226369195-(3,5-Diethoxy-4-iodo-benzyl)-pyrimidine-2,4-diamine

생성물 1

HCID 226368654'-(2,4-Diamino-pyrimidin-5-ylmethyl)-2',6'-diethoxy-biphenyl-4-ol

출처 및 근거

ORD 기록: ord-171415b64b3a4155a2aecda062c47585
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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