2H-1-Benzazepin-2-one, 8-amino-1-ethyl-1,3,4,5-tetrahydro- → {4-[5-Chloro-2-(1-ethyl-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-8-ylamino)-pyrimidin-4-ylamino]-phenyl}-acetonitrile

반응식

[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:18])[c:6]([NH:8][c:9]2[cH:10][cH:11][c:12]([CH2:15][C:16]#[N:17])[cH:13][cH:14]2)[n:7]1.[NH2:19][c:20]1[cH:21][c:22]2[c:23]([cH:32][cH:33]1)[CH2:24][CH2:25][CH2:26][C:27](=[O:31])[N:28]2[CH2:29][CH3:30]>>[c:2]1([NH:19][c:20]2[cH:21][c:22]3[c:23]([cH:32][cH:33]2)[CH2:24][CH2:25][CH2:26][C:27](=[O:31])[N:28]3[CH2:29][CH3:30])[n:3][cH:4][c:5]([Cl:18])[c:6]([NH:8][c:9]2[cH:10][cH:11][c:12]([CH2:15][C:16]#[N:17])[cH:13][cH:14]2)[n:7]1

참가 물질

반응물 2

HCID 98991662H-1-Benzazepin-2-one, 8-amino-1-ethyl-1,3,4,5-tetrahydro-

HCID 79632922[4-(2,5-Dichloro-pyrimidin-4-ylamino)-phenyl]-acetonitrile

생성물 1

HCID 66829927{4-[5-Chloro-2-(1-ethyl-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-8-ylamino)-pyrimidin-4-ylamino]-phenyl}-acetonitrile

출처 및 근거

ORD 기록: ord-d61df6d04348478aaadfa02b4c14cf6f
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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