1-Phenylcyclopropanecarboxylic acid → N-{5-[(7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)carbonyl]pyridin-3-yl}-1-phenylcyclopropanecarboxamide
반응식
[NH2:1][C:2]1[CH:3]=[C:4]([C:8]([C:10]2[C:18]3[CH:17]=[N:16][CH:15]=[N:14][C:13]=3[N:12]([CH3:19])[CH:11]=2)=[O:9])[CH:5]=[N:6][CH:7]=1.[C:20]1([C:26]2([C:29](O)=[O:30])[CH2:28][CH2:27]2)[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[CH3:19][N:12]1[C:13]2[N:14]=[CH:15][N:16]=[CH:17][C:18]=2[C:10]([C:8]([C:4]2[CH:3]=[C:2]([NH:1][C:29]([C:26]3([C:20]4[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=4)[CH2:28][CH2:27]3)=[O:30])[CH:7]=[N:6][CH:5]=2)=[O:9])=[CH:11]1참가 물질
3
실험 절차
The title compound was prepared according to the method described for Library protocol 1 starting from (5-amino-pyridin-3-yl)-(7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-methanone (Preparation 110) and 1-phenylcyclopropanecarboxylic acid to afford the title compound. LCMS: Rt=2.61 min; m/z 398 [M+H]+.
후처리
- customThe title compound was prepared