Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tropic acid → 3-hydroxy-2-phenyl-N-(5-{[7-(propan-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl}pyridin-3-yl)propanamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tropic acid | HCID 10726 | — |
| 반응물 | (5-aminopyridin-3-yl)(7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)methanone | HCID 70817456 | — |
| 생성물 | 3-hydroxy-2-phenyl-N-(5-{[7-(propan-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl}pyridin-3-yl)propanamide | HCID 70817581 | — |
반응 단계
The title compound was prepared according to the method described for Example 167 using (5-aminopyridin-3-yl)(7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)methanone (Preparation 95) and tropic acid to afford the title compound as a yellow solid in 7% yield, 15 mg.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846698B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-97fb3b1a234c446e9eeb928714569d02 |
| 출처 메모 | uspto-grants-2014_09 |