Dichloromethane → [2-Benzyl-4-[4-[1-[(2-methyl-1,3-oxazol-5-yl)methyl]benzimidazol-2-yl]piperazin-1-yl]piperidin-1-yl]-[3,5-bis(trifluoromethyl)phenyl]methanone

HRID 821210노트

반응식

HRID 821210 반응식
[Cl:36][c:37]1[n:38][c:39]2[c:40]([n:41]1[CH2:42][c:43]1[cH:44][n:45][c:46]([CH3:48])[o:47]1)[cH:49][cH:50][cH:51][cH:52]2.[Cl:53][CH2:54][Cl:55].[F:1][C:2]([c:3]1[cH:4][c:5]([C:6](=[O:7])[N:8]2[CH:9]([CH2:20][c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[CH2:10][CH:11]([N:14]3[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]3)[CH2:12][CH2:13]2)[cH:27][c:28]([C:30]([F:31])([F:32])[F:33])[cH:29]1)([F:34])[F:35]>>[F:1][C:2]([c:3]1[cH:4][c:5]([C:6](=[O:7])[N:8]2[CH:9]([CH2:20][c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[CH2:10][CH:11]([N:14]3[CH2:15][CH2:16][N:17]([c:37]4[n:38][c:39]5[c:40]([n:41]4[CH2:42][c:43]4[cH:44][n:45][c:46]([CH3:48])[o:47]4)[cH:49][cH:50][cH:51][cH:52]5)[CH2:18][CH2:19]3)[CH2:12][CH2:13]2)[cH:27][c:28]([C:30]([F:31])([F:32])[F:33])[cH:29]1)([F:34])[F:35]

참가 물질

4

반응물 3

HCID 6344DichloromethaneHCID 186308472-chloro-1-[(2-methyl-5-oxazolyl)methyl]-1H-benzimidazoleHCID 18630855(+/-)-1-[3,5-Bis(trifluoromethyl)benzoyl]-2-(phenylmethyl)-4-(1-piperazinyl)piperidine

생성물 1

HCID 11434025[2-Benzyl-4-[4-[1-[(2-methyl-1,3-oxazol-5-yl)methyl]benzimidazol-2-yl]piperazin-1-yl]piperidin-1-yl]-[3,5-bis(trifluoromethyl)phenyl]methanone

출처 및 근거

ORD 기록
ord-f74ca695570c41d8847fcef08d32f7eb
출처 데이터셋
Test data from https://doi.org/10.1039/C8SC04228D

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