Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(4,6-Dichloropyrimidin-5-yl)acetaldehyde → 7-(2-{[tert-Butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-4-chloro-7H-pyrrolo[2,3-d]pyrimidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (4,6-Dichloropyrimidin-5-yl)acetaldehyde | HCID 13989292 | — |
| 반응물 | 2-tert-Butyldimethylsilyloxy-1,1-dimethylethylamine | HCID 14806740 | — |
| 생성물 | 7-(2-{[tert-Butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-4-chloro-7H-pyrrolo[2,3-d]pyrimidine | HCID 86672073 | — |
반응 단계
The title compound was prepared according to the method described for Preparation 1 using (4,6-dichloropyrimidin-5-yl)acetaldehyde and 1-{[tert-butyl(dimethyl)silyl]oxy}-2-methylpropan-2-amine to afford the title compound as a yellow oil in 38% yield, 377 mg.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846698B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-562544deefd84908947959ec5daa2a20 |
| 출처 메모 | uspto-grants-2014_09 |