4-(Chloromethyl)-1,3-thiazole → N-[2-[4-[3-methyl-4-(1,3-thiazol-4-ylmethoxy)anilino]quinazolin-5-yl]oxypropyl]acetamide

반응식

[Cl:1][CH2:2][c:3]1[n:4][cH:5][s:6][cH:7]1.[OH:8][c:9]1[c:10]([CH3:34])[cH:11][c:12]([NH:15][c:16]2[n:17][cH:18][n:19][c:20]3[cH:21][cH:22][cH:23][c:24]([O:26][CH:27]([CH2:28][NH:29][C:30]([CH3:31])=[O:32])[CH3:33])[c:25]23)[cH:13][cH:14]1>>[CH2:2]([c:3]1[n:4][cH:5][s:6][cH:7]1)[O:8][c:9]1[c:10]([CH3:34])[cH:11][c:12]([NH:15][c:16]2[n:17][cH:18][n:19][c:20]3[cH:21][cH:22][cH:23][c:24]([O:26][CH:27]([CH2:28][NH:29][C:30]([CH3:31])=[O:32])[CH3:33])[c:25]23)[cH:13][cH:14]1

참가 물질

반응물 2

HCID 27632904-(Chloromethyl)-1,3-thiazole

HCID 178474798HCID 178474798, 화합물

생성물 1

HCID 11328734N-[2-[4-[3-methyl-4-(1,3-thiazol-4-ylmethoxy)anilino]quinazolin-5-yl]oxypropyl]acetamide

출처 및 근거

ORD 기록: ord-6b714a5badb74b94ae196c2dc84c7a1a
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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