4-Bromopyrazole → tert-Butyl 2-(4-bromo-1H-pyrazol-1-yl)acetate

반응식

[Br:1][C:2]1[CH:3]=[N:4][NH:5][CH:6]=1.Br[CH2:8][C:9]([O:11][C:12]([CH3:15])([CH3:14])[CH3:13])=[O:10]>>[C:12]([O:11][C:9](=[O:10])[CH2:8][N:4]1[CH:3]=[C:2]([Br:1])[CH:6]=[N:5]1)([CH3:15])([CH3:14])[CH3:13]

참가 물질

반응물 2

HCID 163754-Bromopyrazole

HCID 79177tert-Butyl bromoacetate

생성물 1

HCID 70847699tert-Butyl 2-(4-bromo-1H-pyrazol-1-yl)acetate

실험 절차

The title compound was prepared according to the method described for Preparation 79 using 4-bromo-1H-pyrazole and tert butyl bromoacetate to afford the title compound as a yellow solid in 34% yield, 48.0 g.

후처리

customThe title compound was prepared

출처 및 근거

ORD 기록: ord-f544ae30f3f544d4a27e8809186ee9bc
출처 데이터셋: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08846698B2

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