3-Oxetanamine → 4-Chloro-7-oxetan-3-yl-7H-pyrrolo[2,3-d]pyrimidine

HRID 82178

반응식

HRID 82178 반응식
Cl[C:2]1[C:7]([CH2:8][CH:9]=O)=[C:6]([Cl:11])[N:5]=[CH:4][N:3]=1.[O:12]1[CH2:15][CH:14]([NH2:16])[CH2:13]1>>[Cl:11][C:6]1[C:7]2[CH:8]=[CH:9][N:16]([CH:14]3[CH2:15][O:12][CH2:13]3)[C:2]=2[N:3]=[CH:4][N:5]=1

참가 물질

3

반응물 2

HCID 98339233-OxetanamineHCID 13989292(4,6-Dichloropyrimidin-5-yl)acetaldehyde

생성물 1

HCID 866720984-Chloro-7-oxetan-3-yl-7H-pyrrolo[2,3-d]pyrimidine

실험 절차

The title compound was prepared according to the method described for Preparation 1 using (4,6-dichloropyrimidin-5-yl)acetaldehyde (Preparation 208) and oxetan-3-amine to afford the title compound as a yellow solid in 67% yield, 2.81 g.

후처리

  1. customThe title compound was prepared

출처 및 근거

ORD 기록
ord-da372c854fd145ceb2cc65ad5ec2537d
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08846698B2

연결된 노트

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