Ethyl bromoacetate → Ethyl (5-fluoro-1H-indazol-1-yl)acetate

반응식

[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][N:6]=[CH:5]2.Br[CH2:12][C:13]([O:15][CH2:16][CH3:17])=[O:14]>>[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([CH2:12][C:13]([O:15][CH2:16][CH3:17])=[O:14])[N:6]=[CH:5]2

참가 물질

반응물 2

HCID 7748Ethyl bromoacetate

HCID 178424865-Fluoro-1H-indazole

생성물 1

HCID 70847706Ethyl (5-fluoro-1H-indazol-1-yl)acetate

실험 절차

The title compound was prepared according to the method described for Preparation 93 using 5-fluoro-1H-indazole and ethyl bromoacetate to afford the title compound as an off-white solid in 53% yield, 260 mg.

후처리

customThe title compound was prepared

출처 및 근거

ORD 기록: ord-7e975f13f96047f8b9ac8b988684e57f
출처 데이터셋: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08846698B2

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