Morpholine → N-[4-(2-Furyl)-5-morpholinothiazol-2-yl]-2-morpholinopyridine-4-carboxamide

반응식

[CH2:27]1[CH2:28][O:29][CH2:30][CH2:31][NH:32]1.[CH3:33][N:34]1[CH2:35][CH2:36][CH2:37][C:38]1=[O:39].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([C:8](=[O:9])[NH:10][c:11]2[s:12][c:13]([N:21]3[CH2:22][CH2:23][O:24][CH2:25][CH2:26]3)[c:14](-[c:16]3[o:17][cH:18][cH:19][cH:20]3)[n:15]2)[cH:7]1>>[c:2]1([N:32]2[CH2:27][CH2:28][O:29][CH2:30][CH2:31]2)[n:3][cH:4][cH:5][c:6]([C:8](=[O:9])[NH:10][c:11]2[s:12][c:13]([N:21]3[CH2:22][CH2:23][O:24][CH2:25][CH2:26]3)[c:14](-[c:16]3[o:17][cH:18][cH:19][cH:20]3)[n:15]2)[cH:7]1

참가 물질

반응물 3

HCID 8083Morpholine

HCID 13387N-methyl-2-pyrrolidone

HCID 231441232-Chloro-N-[4-(2-furyl)-5-morpholinothiazol-2-yl]pyridine-4-carboxamide

생성물 1

HCID 23144302N-[4-(2-Furyl)-5-morpholinothiazol-2-yl]-2-morpholinopyridine-4-carboxamide

출처 및 근거

ORD 기록: ord-6d3ebeb832cf482d8de45a95f14b5818
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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