Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ether, ethyl ethynyl → [2-Chloro-5-((E)-2-ethoxy-vinyl)-pyrimidin-4-yl]-(2-methoxy-1,1-dimethyl-ethyl)-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ether, ethyl ethynyl | HCID 61239 | — |
| 반응물 | Benzcatechinborane | HCID 6327445 | — |
| 반응물 | (5-Bromo-2-chloro-pyrimidin-4-yl)-(2-methoxy-1,1-dimethyl-ethyl)-amine | HCID 86672124 | — |
| 생성물 | [2-Chloro-5-((E)-2-ethoxy-vinyl)-pyrimidin-4-yl]-(2-methoxy-1,1-dimethyl-ethyl)-amine | HCID 86672125 | — |
반응 단계
The title compound was prepared according to the method described for Preparation 61 using (5-Bromo-2-chloro-pyrimidin-4-yl)-(2-methoxy-1,1-dimethyl-ethyl)-amine (Preparation 256), catechol borane and ethoxyacetylene (40% in hexane) to afford the title compound as light brown gum in 44% yield, 2.6 g.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846698B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-1ce22986ba4a440495b30bf3ade47f58 |
| 출처 메모 | uspto-grants-2014_09 |