Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanol → Ethyl 4-nitrophenylacetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | (4-Nitrophenyl)acetic acid | HCID 4661 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 생성물 | Ethyl 4-nitrophenylacetate | HCID 79517 | 98% |
반응 단계
To a stirred solution of (4-nitro-phenyl)-acetic acid (3 g, 16.4 mmol) in ethanol (30 mL) was added sulphuric acid (1 mL) and the reaction mixture was heated to reflux for 16 hours. The reaction mixture was neutralized with 2N aq. NaOH solution and extracted with EtOAc (3×50 mL). The combined organic layers were dried (Na2SO4) and evaporated in vacuo to afford the title compound as a light yellow oil in 98% yield, 3.4 g.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846698B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-6b9f9ab498404a8ab71a0ea8bcffc870 |
| 출처 메모 | uspto-grants-2014_09 |