Pyridine → 2-(4-(3-Fluorophenylsulfonamido)phenyl)-3,3-dimethyl-1,2,3,4-tetrahydroquinoline-6-carboxylic acid

반응식

[F:23][c:24]1[cH:25][c:26]([S:30](=[O:31])(=[O:32])[Cl:33])[cH:27][cH:28][cH:29]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[NH:9][c:10]3[cH:11][cH:12][c:13]([C:20](=[O:21])[OH:22])[cH:14][c:15]3[CH2:16][C:17]2([CH3:18])[CH3:19])[cH:6][cH:7]1.[cH:34]1[cH:35][cH:36][n:37][cH:38][cH:39]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([CH:8]2[NH:9][c:10]3[cH:11][cH:12][c:13]([C:20](=[O:21])[OH:22])[cH:14][c:15]3[CH2:16][C:17]2([CH3:18])[CH3:19])[cH:6][cH:7]1)[S:30]([c:26]1[cH:25][c:24]([F:23])[cH:29][cH:28][cH:27]1)(=[O:31])=[O:32]

참가 물질

반응물 3

HCID 1049Pyridine

HCID 27342583-Fluorobenzenesulfonyl Chloride

HCID 674414332-(4-Aminophenyl)-3,3-dimethyl-1,2,3,4-tetrahydroquinoline-6-carboxylic acid

생성물 1

HCID 584761442-(4-(3-Fluorophenylsulfonamido)phenyl)-3,3-dimethyl-1,2,3,4-tetrahydroquinoline-6-carboxylic acid

출처 및 근거

ORD 기록: ord-f2a298008c47455d89ae7e1b07d20788
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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