1-Methylpyrrolidine → 1-Cyano-4-hydroxy-7-(4-methoxy-phenoxy)-isoquinoline-3-carboxylic acid butyl ester

반응식

[CH2:1]([CH2:2][CH2:3][CH3:4])[O:5][C:6](=[O:7])[c:8]1[n:9][c:10]([Br:28])[c:11]2[cH:12][c:13]([O:19][c:20]3[cH:21][cH:22][c:23]([O:26][CH3:27])[cH:24][cH:25]3)[cH:14][cH:15][c:16]2[c:17]1[OH:18].[CH3:32][N:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1.[Cu:29][C:30]#[N:31]>>[CH2:1]([CH2:2][CH2:3][CH3:4])[O:5][C:6](=[O:7])[c:8]1[n:9][c:10]([C:30]#[N:31])[c:11]2[cH:12][c:13]([O:19][c:20]3[cH:21][cH:22][c:23]([O:26][CH3:27])[cH:24][cH:25]3)[cH:14][cH:15][c:16]2[c:17]1[OH:18]

참가 물질

반응물 3

HCID 84541-Methylpyrrolidine

HCID 866170761-Bromo-4-hydroxy-7-(4-methoxy-phenoxy)-isoquinoline-3-carboxylic acid butyl ester

HCID 178418546HCID 178418546, 화합물

생성물 1

HCID 671104471-Cyano-4-hydroxy-7-(4-methoxy-phenoxy)-isoquinoline-3-carboxylic acid butyl ester

출처 및 근거

ORD 기록: ord-950eb97ec9c44461ba7bb0eeff51d82e
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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