Water → 5-[4-(3-chloro-4-fluoro-phenylamino)-2-oxo-1,2-dihydro-pyrrolo [2,3-b]pyridin-3-ylidenemethyl]-4-methyl-1H-pyrrole-2-carboxylic acid (2-morpholin-4-yl-ethyl)-amide

HRID 825167노트

반응식

[CH3:51][O:52][CH2:53][CH2:54][O:55][CH2:56][CH2:57][O:58][CH3:59].[Cl:30][c:31]1[cH:32][c:33]([NH2:38])[cH:34][cH:35][c:36]1[F:37].[O:1]1[CH2:2][CH2:3][N:4]([CH2:7][CH2:8][NH:9][C:10](=[O:11])[c:12]2[nH:13][c:14]([CH:18]=[C:19]3[C:20](=[O:29])[NH:21][c:22]4[n:23][cH:24][cH:25][c:26]([Cl:28])[c:27]43)[c:15]([CH3:17])[cH:16]2)[CH2:5][CH2:6]1.[OH2:39].[c:40]1([CH3:41])[cH:42][cH:43][c:44]([S:45]([OH:46])(=[O:47])=[O:48])[cH:49][cH:50]1>>[O:1]1[CH2:2][CH2:3][N:4]([CH2:7][CH2:8][NH:9][C:10](=[O:11])[c:12]2[nH:13][c:14]([CH:18]=[C:19]3[C:20](=[O:29])[NH:21][c:22]4[n:23][cH:24][cH:25][c:26]([NH:38][c:33]5[cH:32][c:31]([Cl:30])[c:36]([F:37])[cH:35][cH:34]5)[c:27]43)[c:15]([CH3:17])[cH:16]2)[CH2:5][CH2:6]1