3-(Chloromethyl)-5-(3,5-dimethylisoxazol-4-yl)-1,2,4-oxadiazole → 1-{[5-(3,5-Dimethyl-4-isoxazolyl)-1,2,4-oxadiazol-3-yl]methyl}-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

반응식

[CH3:1][c:2]1[nH:3][c:4]2[cH:5][cH:6][c:7]([C:15]#[N:16])[c:8]([C:11]([F:12])([F:13])[F:14])[c:9]2[cH:10]1.[Cl:17][CH2:18][c:19]1[n:20][o:21][c:22](-[c:24]2[c:25]([CH3:30])[n:26][o:27][c:28]2[CH3:29])[n:23]1>>[CH3:1][c:2]1[n:3]([CH2:18][c:19]2[n:20][o:21][c:22](-[c:24]3[c:25]([CH3:30])[n:26][o:27][c:28]3[CH3:29])[n:23]2)[c:4]2[cH:5][cH:6][c:7]([C:15]#[N:16])[c:8]([C:11]([F:12])([F:13])[F:14])[c:9]2[cH:10]1

참가 물질

반응물 2

HCID 27357603-(Chloromethyl)-5-(3,5-dimethylisoxazol-4-yl)-1,2,4-oxadiazole

HCID 533093462-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

생성물 1

HCID 674048311-{[5-(3,5-Dimethyl-4-isoxazolyl)-1,2,4-oxadiazol-3-yl]methyl}-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

출처 및 근거

ORD 기록: ord-06339e3997f84d6ca8f1b205741aa3c9
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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