Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 3-Amino-2-chloro-4-methylpyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Hydrogen Peroxide | HCID 784 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 3-Amino-4-picoline | HCID 137935 | — |
| 생성물 | 3-Amino-2-chloro-4-methylpyridine | HCID 2756387 | — |
반응 단계
A mixture of 4-methylpyridin-3-amine (0.62 g), 12N hydrogen chloride (3.8 mL) and 30% hydrogen peroxide (0.75 mL) was stirred at 0° C. to room temperature for 1 h. The mixture was neutralized with K2CO3, and the mixture was extracted with AcOEt. The organic layer was dried over MgSO4, and concentrated in vacuo to give 2-chloro-4-methylpyridin-3-amine (0.75 g) as an orange solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846713B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-489da6a3a71449b29daba86270409920 |
| 출처 메모 | uspto-grants-2014_09 |