Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl iodide → HCID 178503348, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl iodide | HCID 6328 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | HCID 178527819 | HCID 178527819 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | HCID 178503348 | HCID 178503348 | 45.8% |
반응 단계
To a solution of 1H-imidazo[4,5-b]pyridine-2-thiol (2 g) in acetone (30 mL) were added MeI (0.910 ml) and K2CO3 (5.48 g) at room temperature. After stirring for 10 h, the mixture was concentrated under reduced pressure. The residue was purified by column chromatography (NH-silica gel, eluted with 10%-100% EtOAc in hexane) to give 2-(methylsulfanyl)-3H-imidazo[4,5-b]pyridine (1.0 g) as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846713B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-552e96a795fb4545bccf28eb5db15d6d |
| 출처 메모 | uspto-grants-2014_09 |