Acetyl chloride → (2'-{[Acetyl-(2,2,2-trifluoro-ethyl)-amino]-methyl}-6-fluoro-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester

반응식

[CH3:1][O:2][C:3]([CH2:4][c:5]1[cH:6][c:7](-[c:12]2[c:13]([CH2:22][NH:23][CH2:24][C:25]([F:26])([F:27])[F:28])[cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]2)[c:8]([F:11])[cH:9][cH:10]1)=[O:29].[CH3:30][C:31]([Cl:32])=[O:33]>>[CH3:1][O:2][C:3]([CH2:4][c:5]1[cH:6][c:7](-[c:12]2[c:13]([CH2:22][N:23]([CH2:24][C:25]([F:26])([F:27])[F:28])[C:31]([CH3:30])=[O:33])[cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]2)[c:8]([F:11])[cH:9][cH:10]1)=[O:29]

참가 물질

반응물 2

HCID 6367Acetyl chloride

HCID 86633170{6-Fluoro-2'-[(2,2,2-trifluoro-ethylamino)-methyl]-4'-trifluoromethyl-biphenyl-3-yl}acetic acid methyl ester

생성물 1

HCID 86651103(2'-{[Acetyl-(2,2,2-trifluoro-ethyl)-amino]-methyl}-6-fluoro-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester

출처 및 근거

ORD 기록: ord-fe431bf5773945768c3ba97cfeed33d0
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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