3-Bromo-4-fluoroaniline → 4-Amino-N-(3-bromo-4-fluorophenyl)isothiazole-3-carboxamide

HRID 82722

반응식

HRID 82722 반응식
Cl.[NH2:2][C:3]1[C:4]([C:8]([OH:10])=O)=[N:5][S:6][CH:7]=1.[Br:11][C:12]1[CH:13]=[C:14]([CH:16]=[CH:17][C:18]=1[F:19])[NH2:15]>>[NH2:2][C:3]1[C:4]([C:8]([NH:15][C:14]2[CH:16]=[CH:17][C:18]([F:19])=[C:12]([Br:11])[CH:13]=2)=[O:10])=[N:5][S:6][CH:7]=1

참가 물질

3

반응물 2

HCID 27792863-Bromo-4-fluoroanilineHCID 66031414-Aminoisothiazole-3-carboxylic acid hydrochloride

생성물 1

HCID 585584334-Amino-N-(3-bromo-4-fluorophenyl)isothiazole-3-carboxamide

실험 절차

This compound was prepared according to the procedure of Example 44, Step 1, using 4-aminoisothiazole-3-carboxylic acid hydrochloride and 3-bromo-4-fluoroaniline as the starting materials. LCMS for C10H8BrFN3OS (M+H)+: m/z=315.9, 317.9.

후처리

  1. customThis compound was prepared

출처 및 근거

ORD 기록
ord-1ed9d390b7434e1eb5166e5affa56052
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08846726B2

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