Dichloromethane → N-(1-(3-fluoro-4-hydroxyphenyl)-5-oxopyrrolidin-3-yl)benzamide

반응식

[B:25]([Br:26])([Br:27])[Br:28].[Cl:29][CH2:30][Cl:31].[F:1][c:2]1[cH:3][c:4]([N:10]2[CH2:11][CH:12]([NH:16][C:17]([c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)=[O:24])[CH2:13][C:14]2=[O:15])[cH:5][cH:6][c:7]1[O:8][CH3:9]>>[F:1][c:2]1[cH:3][c:4]([N:10]2[CH2:11][CH:12]([NH:16][C:17]([c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)=[O:24])[CH2:13][C:14]2=[O:15])[cH:5][cH:6][c:7]1[OH:8]

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 25134Boron tribromide

HCID 68419077N-(1-(3-fluoro-4-methoxyphenyl)-5-oxopyrrolidin-3-yl)benzamide

생성물 1

HCID 68421403N-(1-(3-fluoro-4-hydroxyphenyl)-5-oxopyrrolidin-3-yl)benzamide

출처 및 근거

ORD 기록: ord-0b76a1eeb5d443618384d9616d956265
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…